Recommended Open-source stack Open-source stack Layer Recommended Options LLMs LLaMA 4, Qwen 3, Mixtral, DeepSeek Fast Inference Groq, vLLM, Ollama Agent Framework LlamaIndex Workflow Engine LlamaIndex Workflows API Layer FastAPI Vector DB Qdrant, Chroma Graph DB Neo4j, Memgraph SQL DB PostgreSQL Policy Engine OPA (Open Policy Agent) / Cedar Observability Langfuse / OpenTelemetry Queueing Redis / Kafka Automation N8N Auth OAuth2 / Keycloak Tool interoperability  MCP (Model Context Protocol) — now under the Agentic AI Foundation / Linux Foundation Agent memory  Mem0, Zep, or a self-hosted tiered store (working / episodic / semantic) NEW IN 2026  Anthropic donated MCP to the newly formed Agentic AI Foundation under the Linux Foundation in December 2025, with OpenAI and Block as co-founders and AWS, Google, Microsoft, Cloudflare, GitHub, and Bloomberg as supporting members. It is now a vendor-neutral standard rather than a single-vendor protocol, which is why it belongs in the stack table above rather than only in the tool layer section.   Recommended Winning Stack (2026) Layer Choice API FastAPI Agent Framework LlamaIndex Workflow LlamaIndex Workflows Tool Interoperability MCP (2026-07-28 spec, stateless) Vector Memory ChromaDB Graph Memory Neo4j Agent Memory Layer Mem0 / Zep (tiered, benchmarked) SQL PostgreSQL Models Groq / vLLM served OSS models Policies OPA Observability Langfuse + OpenTelemetry Queue Redis Automation N8N